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Updated: Jul 30, 2025

Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review
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Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review

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Mass: The Conundrum in Spine.

P D Rath1, Sunil Katoch2, Abhijeet Kumar Agrawal1

  • 1Department of Rheumatology, Max Healthcare, Saket, New Delhi, India.

Journal of Orthopaedic Case Reports
|May 16, 2023
PubMed
Summary
This summary is machine-generated.

Immunoglobulin (IgG4)-related disease is a rare condition that can affect the central nervous system, particularly the spinal cord. Diagnosis relies on histopathology, crucial for managing this rare IgG4-related spinal cord disease.

Keywords:
IgG4central nervous systempleuraspinal mass

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Area of Science:

  • Rheumatology
  • Neurology
  • Pathology

Background:

  • Immunoglobulin (IgG4)-related disease is a rare systemic condition affecting multiple organs.
  • Central nervous system involvement is uncommon, with spinal cord presentation being exceptionally rare.

Observation:

  • Two cases of IgG4-related disease involving the spinal cord are presented.
  • Case 1: A 50-year-old male with spinal cord compression due to a dural mass positive for IgG4.
  • Case 2: A 65-year-old female with paravertebral soft-tissue thickening compatible with IgG4 disease.

Findings:

  • Histopathological examination is critical for diagnosing IgG4-related disease.
  • The presented cases highlight the rarity of spinal cord involvement in IgG4-related disease.
  • Diagnosis of IgG4-related spinal cord disease requires careful histopathological analysis.

Implications:

  • Accurate diagnosis through histopathology is essential for effective management and prognosis of IgG4-related disease.
  • Spinal cord manifestations of IgG4-related disease require prompt recognition and treatment to prevent recurrence.
  • This study underscores the importance of considering IgG4-related disease in the differential diagnosis of spinal cord lesions.