Age-related decrease in electrical coupling of two identified neurons in the mollusc Lymnaea stagnalis

Electrophysiological characteristics of two identified giant electrotonically coupled neurosecretory cells in the central nervous system of the mollusc Lymnaea stagnalis were studied in mature animals of different age. The coupling coefficient of the neurons decreased considerably with age. The possibility that the decrease is due to an increase in the junctional resistance between the cells is discussed.