Myocardial infarction in a 33-year-old with inflammatory bowel disease: a case report
Christopher Paul Bengel1, Denisa Müller-Gastell2, Bassam Al-Najjar2
1Department of Cardiology, Frankfurt-Main-Taunus Clinics, Bad Soden Hospital, Kronberger Str. 36, 65812, Bad Soden, Germany. cbengel@kliniken-mtk.de.
Insights
ST elevation myocardial infarction (STEMI) can occur in patients with normal coronary arteries, potentially linked to hypercoagulable states from systemic inflammation, as seen in inflammatory bowel disease.
Area of Science:
- Cardiology
- Gastroenterology
- Hematology
Background:
- ST elevation myocardial infarction (STEMI) involves acute myocardial injury and necrosis due to ischemia, often caused by atherosclerotic coronary artery thrombosis.
- Thromboembolism can precipitate myocardial infarction even in individuals with normal coronary arteries.
Background:
ST elevation myocardial infarction is defined as acute myocardial injury with necrosis due to myocardial ischemia. The frequent cause is thrombotic occlusion of atherosclerotic coronary arteries. In particular situations, thromboembolism can cause myocardial infarction in patients with normal coronary arteries.
Case Presentation:
We report a particular case of myocardial infarction in a young, previously healthy patient with non-atherosclerotic coronary arteries and inflammatory bowel disease. Although we performed an extensive work up, no clear pathophysiological cause could be diagnosed. Most likely, myocardial infarction was associated with a hypercoagulative state related to systemic inflammation.
Conclusion:
The mechanisms of coagulation disturbances in the context of acute and chronic inflammation are not yet fully understood. A better understanding of cardiovascular events in patients with inflammatory bowel disease might lead to new treatment approaches of cardiovascular disease.
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