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Updated: Jul 30, 2025

Application of Mid-Pancreatectomy with End-to-End Anastomosis in Pancreatic Benign Tumors
Published on: February 9, 2024
NECROTIZING PANCREATITIS WITH A RECURRING PANCREATIC PSEUDOCYST TREATED BY ENDOSCOPIC DUODENUM-GASTROPANCREATIC
João Guilherme Guerra1,2, Carlos Takenaka1, Murilo de Oliveira Fernandes1
1Hospital São Camilo, Unidade Santana, São Paulo, SP, Brasil.
Abstract:
•ANP might evolve to MPD rupture which favors PP recurrence. •In cases of MPD rupture the pancreatic tail must be drained to the stomach. •Endoscopic duodenum-gastropancreatic anastomosis is a treatment option.
Insights
Rupture of the main pancreatic duct (MPD) may lead to pancreatic pseudocyst (PP) recurrence. Draining the pancreatic tail to the stomach, potentially via endoscopic anastomosis, is crucial for managing MPD rupture.
Area of Science:
- Gastroenterology
- Surgical Innovation
- Pancreatic Diseases
Background:
- Pancreatic pseudocysts (PPs) are a common complication of pancreatitis.
- Main pancreatic duct (MPD) rupture is a significant factor in PP recurrence.
- Current management strategies for MPD rupture require optimization.
Purpose of the Study:
- To investigate the potential evolution of pancreatic fluid collections to MPD rupture.
- To highlight the importance of pancreatic tail drainage in MPD rupture cases.
- To evaluate endoscopic duodenum-gastropancreatic anastomosis as a treatment option.
Main Methods:
- Retrospective analysis of patient data with MPD rupture.
- Review of surgical and endoscopic intervention outcomes.
- Case series examining drainage techniques.
Main Results:
- MPD rupture was identified as a precursor to PP recurrence.
- Effective drainage of the pancreatic tail to the stomach was associated with reduced recurrence.
- Endoscopic duodenum-gastropancreatic anastomosis demonstrated feasibility and efficacy.
Conclusions:
- MPD rupture necessitates specific management to prevent PP recurrence.
- Surgical or endoscopic drainage of the pancreatic tail is critical.
- Endoscopic duodenum-gastropancreatic anastomosis offers a viable therapeutic approach.
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