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Recent advances in horizontal alveolar bone regeneration
Tiancheng Li1,2, Xinyi Zeng1, Shujuan Zou1
1State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Biomedical Materials (Bristol, England)
|May 17, 2023
Summary
Horizontal alveolar bone loss, common in periodontitis, presents challenges for regeneration. This review explores recent advances, obstacles, and future strategies for effective periodontal bone regeneration.
Area of Science:
- Periodontology
- Biomaterials Science
- Regenerative Medicine
Background:
- Alveolar bone loss is a prevalent issue affecting periodontal health across all age groups.
- Horizontal alveolar bone loss is the predominant pattern observed in periodontitis.
- Current regenerative therapies for horizontal alveolar bone defects are limited and unpredictable.
Purpose of the Study:
- To review recent advancements in horizontal alveolar bone regeneration.
- To discuss biomaterials and approaches used in preclinical and clinical settings for horizontal bone regeneration.
- To identify current challenges and future directions for effective regenerative strategies.
Main Methods:
- Literature review of recent advances in horizontal alveolar bone regeneration.
- Discussion of biomaterials and therapeutic approaches (clinical and preclinical).
- Analysis of existing obstacles and future research avenues.
Main Results:
- Limited regenerative procedures are currently available for horizontal alveolar bone loss.
- Various biomaterials and approaches have been investigated, with varying success.
- Significant obstacles remain in achieving predictable regeneration of horizontal defects.
Conclusions:
- Horizontal alveolar bone loss is a challenging periodontal defect type.
- Further research into novel biomaterials and multidisciplinary strategies is crucial.
- Developing predictable regenerative therapies is essential for improving periodontal health outcomes.
