An Inflection Point in Cancer Protein Biomarkers: What was and What's Next

Anna D Barker1, Mario M Alba2, Parag Mallick3

  • 1Lawrence J. Ellison Institute for Transformative Medicine, Los Angeles, California, USA; Complex Adaptive Systems Initiative and School of Life Sciences, Arizona State University, Tempe, Arizona, USA.

Summary

Biomarker discovery in cancer medicine needs a paradigm shift. Redefining biomarkers as representations of complex biological system states, integrating multi-omics and advanced technologies, can improve cancer therapy selection and patient monitoring.

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