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Cannabinoids as multifaceted compounds.

Diana Persia1, Francesca Mangiavacchi2, Maria Carla Marcotullio1

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Summary
This summary is machine-generated.

Cannabis and cannabinoids, once restricted, are now researched for medical use due to the discovery of the endocannabinoid system. Global regulations vary, impacting therapeutic applications and product development.

Keywords:
CBDCannabinoid receptorsCannabinoidsChemistryEndocannabinoid systemNPSPharmacologySCRAsTHC

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Area of Science:

  • Pharmacology
  • Phytochemistry
  • Medical Chemistry

Background:

  • Cannabis has historical uses, but legislation restricted it post-1930s due to psychoactive effects.
  • The discovery of the endocannabinoid system and its role in homeostasis has revealed new therapeutic targets.
  • Renewed interest in medical cannabis necessitates understanding its complex regulatory landscape.

Purpose of the Study:

  • To provide an overview of current research on cannabinoids.
  • To explore the multidisciplinary fields involved in cannabinoid research, including chemistry, phytochemistry, pharmacology, and analytics.
  • To highlight the heterogeneity of global regulations surrounding cannabis and cannabinoid products.

Main Methods:

  • Literature review of research on cannabis and cannabinoids.
  • Analysis of pharmacological activities and therapeutic potential.
  • Examination of regulatory frameworks across different countries.

Main Results:

  • Cannabinoids show potential for treating various pathological disorders.
  • Significant advancements have been made in understanding the endocannabinoid system.
  • There is a wide variation in legal regulations concerning cannabis and cannabinoid products globally.

Conclusions:

  • Cannabinoids offer promising therapeutic avenues, driven by recent scientific discoveries.
  • Further research is needed to fully elucidate the pharmacological properties and applications of cannabinoids.
  • Harmonization of international regulations is crucial for the safe and effective use of cannabis-based medicines.