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Cross-stream migration of a vesicle in vortical flows
Gökberk Kabacaoğlu1, Enkeleida Lushi2
1Department of Mechanical Engineering, İhsan Doğramacı Bilkent University Ankara, 06800, Turkey.
Physical Review. E
|May 18, 2023
Summary
Numerical simulations reveal how deformable vesicles behave in Taylor-Green vortex flow. Highly deformable vesicles move inward, while less deformable ones migrate outward, a novel phenomenon with potential microfluidic applications.
Area of Science:
- Fluid dynamics
- Biophysics
- Computational science
Background:
- Vesicles, deformable membrane-bound sacs, are essential models for biological cells like red blood cells.
- Previous studies explored vesicle dynamics in various flows (shear, Poiseuille, Taylor-Couette), but Taylor-Green vortex flow presents unique complexities.
- Taylor-Green vortices exhibit non-uniform flow curvature and shear gradients, necessitating detailed investigation of vesicle behavior.
Purpose of the Study:
- To systematically investigate vesicle dynamics within 2D Taylor-Green vortex flow under inertialess conditions.
- To analyze the influence of interior-to-exterior viscosity ratio and capillary number on vesicle deformability and migration patterns.
- To identify novel migration behaviors and their potential applications.
Main Methods:
- Utilizing numerical simulations to model vesicle behavior in a 2D Taylor-Green vortex flow.
- Systematically varying key parameters: viscosity ratio and capillary number (shear forces to membrane stiffness).
- Analyzing vesicle trajectories, deformability, and rotational behavior within the simulated flow.
Main Results:
- Vesicle deformability is found to be a nonlinear function of the studied parameters.
- Sufficiently deformable vesicles migrate towards and rotate at the vortex center.
- Less deformable vesicles exhibit outward migration from the vortex center, a previously unobserved phenomenon in this flow type.
Conclusions:
- The study elucidates complex vesicle dynamics in Taylor-Green vortex flow, driven by deformability.
- Outward migration of vesicles in this flow regime is a novel finding with significant implications.
- Observed cross-streamline migration phenomena offer potential for applications in microfluidic cell separation technologies.
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