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First uterine transplant case at the Royal Prince Alfred Hospital
Dana Georgevsky1,2, Li Ying1, Surya Krishnan1
1Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
Summary
Uterine transplantation (UT) offers a new path for women with absolute uterine factor infertility (AUFI). A recent surgery at RPAH successfully transplanted a uterus from a living unrelated donor, with both patients recovering well.
Area of Science:
- Reproductive Medicine
- Transplant Surgery
Background:
- Absolute uterine factor infertility (AUFI) affects women unable to carry a pregnancy.
- Uterine transplantation (UT) is an emerging treatment option for AUFI.
- The Royal Prince Alfred Hospital (RPAH) initiated a UT program in 2019, which was paused due to the COVID-19 pandemic.
Observation:
- RPAH performed its first uterine transplant in February 2023.
- The transplant involved a living unrelated donor and a 25-year-old recipient with Mayer-Rokitansky-Küster-Hauser syndrome.
- Both donor and recipient surgeries were uncomplicated.
Findings:
- The early post-operative recovery for both the donor and recipient is progressing well.
- This marks a significant milestone for the RPAH UT program.
Implications:
- Successful UT procedures offer hope for women with AUFI to achieve pregnancy and childbirth.
- This case demonstrates the feasibility of UT from living unrelated donors.
- Continued research and clinical application of UT could expand reproductive options for infertile women.
