Empyema with an extensive retroperitoneal abscess after the first dose of the COVID-19 vaccine, a case report

Seyed Amir Miratashi Yazdi1, Nasim Eshraghi2, Samira Mirzaei3

  • 1Department of Surgery, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Abstract

Insights

A rare retroperitoneal abscess developed in a patient after COVID-19 vaccination. This case highlights the importance of monitoring uncommon vaccine side effects.

Area of Science:

  • Medicine
  • Infectious Diseases
  • Vaccinology

Background:

  • COVID-19 vaccination is associated with common, mild side effects like injection site pain and fever.
  • Retroperitoneal abscess is a rare but serious condition with high mortality, often presenting with subtle symptoms.

Observation:

  • A 29-year-old male presented with dyspnea, chest, and abdominal pain post-first COVID-19 vaccine dose.
  • Initial findings included a lung abscess that had ruptured into the pleural space, requiring thoracotomy.
  • Subsequent imaging revealed a retroperitoneal abscess, necessitating surgical drainage.

Findings:

  • This case presents a rare instance of a retroperitoneal abscess potentially linked to COVID-19 vaccination.
  • The patient experienced severe symptoms beyond typical vaccine side effects, leading to complex surgical interventions.

Implications:

  • Healthcare providers should be vigilant for rare and severe adverse events following vaccination.
  • Further surveillance is crucial to determine potential associations between COVID-19 vaccines and uncommon complications like retroperitoneal abscess.

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