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Updated: Jul 30, 2025

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
A case of eosinophilic bronchiolitis after the initiation of immune checkpoint inhibitor
Akiko Tamura1, Masao Hashimoto1, Atsuko Hosoi2
1National Center for Global Health and Medicine Hospital, Respiratory Medicine, Tokyo, Japan.
Abstract:
A 50-year-old Japanese woman with advanced breast cancer presented with productive cough and dyspnea while she was receiving a sixth cycle of chemotherapy including atezolizumab. Chest computed tomography revealed bronchiolitis and transbronchial lung cryobiopsy revealed eosinophilic bronchiolitis. Corticosteroid therapy successfully resolved her symptoms. Eosinophilic bronchiolitis is a rare but important immune-related adverse event; herein, we discuss its diagnosis and possible pathophysiology.
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