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Sympathetic nervous system and dysfunction of the lower urinary tract
Clinical Science (London, England : 1979)
|January 1, 1986
Summary
This study identifies patients with prostatodynia, also known as anxious bladder syndrome, showing consistent psychophysiological and urodynamic results. While suggesting sympathetic nervous system involvement, direct proof of adrenergic mechanisms causing bladder dysfunction remains elusive.
Area of Science:
- Urology
- Neuroscience
- Physiology
Background:
- Prostatodynia, or anxious bladder syndrome, is characterized by underactive detrusor function.
- Previous research suggests a potential role for the sympathetic nervous system in bladder and urethral function.
Purpose of the Study:
- To identify a homogeneous group of patients with prostatodynia.
- To investigate the psychophysiological and urodynamic characteristics of these patients.
- To explore the potential role of the sympathetic nervous system in the observed bladder dysfunction.
Main Methods:
- Utilized careful clinical and investigative protocols for patient selection.
- Conducted psychophysiological studies.
- Performed urodynamic measurements.
Main Results:
- Successfully identified a homogeneous group of patients with prostatodynia.
- Demonstrated remarkably consistent psychophysiological and urodynamic results within this patient group.
- Results support, but do not definitively prove, the hypothesis of sympathetic nervous system influence on bladder function.
Conclusions:
- A consistent patient profile for prostatodynia (anxious bladder syndrome) was established.
- Findings indicate a potential link between the sympathetic nervous system and bladder/urethral dysfunction.
- Objective proof for direct adrenergic mechanism involvement in prostatodynia was not obtained.