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Total and regional dual X-ray absorptiometry derived four-compartment model
Madeline A Czeck1, William T Juckett1, Erica J Roelofs1
1School of Kinesiology, University of Minnesota, Minneapolis, MN, 55455, USA.
Clinical Nutrition ESPEN
|May 18, 2023
Summary
Dual X-ray absorptiometry (DXA) software enables a convenient regional four-compartment model for body composition analysis. This validated method accurately estimates fat mass, fat-free mass, and percent fat using DXA-derived volume.
Area of Science:
- Body composition analysis
- Dual X-ray absorptiometry (DXA)
- Four-compartment modeling
Background:
- Dual X-ray absorptiometry (DXA) software enables body composition assessment.
- Recent advancements allow DXA-derived volume estimation.
- DXA-derived volume facilitates a convenient four-compartment model for accurate body composition measurement.
Purpose of the Study:
- To evaluate the validity of a regional DXA-derived four-compartment model.
- To assess the accuracy of DXA-derived volume in body composition analysis.
- To establish a convenient method for regional body composition assessment.
Main Methods:
- 30 participants underwent DXA scans, underwater weighing, and bioelectrical impedance spectroscopy.
- Regional DXA body composition was assessed using manually created region of interest boxes.
- Linear regression models and Repeated k-fold Cross Validation were used to create and validate regional four-compartment models.
Main Results:
- Regional DXA-derived four-compartment models for arms and legs showed no significant differences in fat mass, fat-free mass, or percent fat compared to water displacement methods.
- Cross-validation yielded R-squared values of 0.669 for the arm and 0.783 for the leg.
- The DXA-derived models accurately estimated regional body composition parameters.
Conclusions:
- Dual X-ray absorptiometry (DXA) can be utilized to develop a four-compartment model for estimating total and regional body composition.
- The study validates a convenient regional four-compartment model using DXA-derived regional volume.
- This approach offers a practical method for accurate regional body composition analysis.
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