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The Relationship Between Exercise, Cathepsin B, and Cognitive Functions: Systematic Review
1Physical Therapy and Rehabilitation Hospital, Sports Rehabilitation Laboratory, Ankara City Hospital, Ankara, Turkey.
Perceptual and Motor Skills
|May 18, 2023
Summary
Regular exercise may enhance cognitive functions by influencing peripheral Cathepsin B (CTSB) levels. This review explores the link between physical activity, CTSB, and cognitive performance, suggesting a potential mechanism for exercise-induced brain benefits.
Area of Science:
- Neuroscience
- Exercise Physiology
- Biochemistry
Background:
- Exercise is recognized for its cognitive benefits.
- Peripheral signal molecules are implicated in exercise-induced cognitive improvements.
- Cathepsin B (CTSB) is a key enzyme in cellular processes.
Conclusions:
- Exercise may play a role in modulating peripheral Cathepsin B levels, potentially contributing to cognitive improvements.
- Further high-quality research is necessary to elucidate the precise mechanisms underlying the relationship between exercise, CTSB, and cognitive performance.
- Understanding this link could offer new insights into exercise-based interventions for cognitive health.

