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HTNpedia: A Knowledge Base for Hypertension Research

Lakshmanan Loganathan1, Jeyakanthan Jeyaraman1, Karthikeyan Muthusamy1

  • 1Department of Bioinformatics, Alagappa University, Karaikudi, 630003, Tamil Nadu, India.

Combinatorial Chemistry & High Throughput Screening
|May 19, 2023
PubMed

Insights

Hypertension, a major health issue, now has a dedicated knowledge base called HTNpedia. This resource provides vital information on hypertension-related genes and proteins for researchers and the public.

Area of Science:

  • Biomedical Informatics
  • Genomics
  • Cardiovascular Research

Background:

  • Hypertension is a significant global health concern, linked to cardiovascular disease and renal failure.
  • It is the fourth leading cause of worldwide mortality.
  • Existing resources lack a comprehensive database for hypertension and related conditions.

Purpose of the Study:

  • To address the absence of a centralized knowledge base for hypertension.
  • To create an accessible platform for hypertension-related information.

Main Methods:

  • Utilized research outputs from an active hypertension research laboratory.
  • Compiled a preliminary dataset of hypertension-related genes and proteins.
  • Provided external links to a public repository for further analysis.

Main Results:

  • Developed HTNpedia, a novel online resource.
  • HTNpedia offers information on hypertension-associated proteins and genes.
  • The platform aims to support research and understanding of hypertension.

Conclusions:

  • HTNpedia is now publicly accessible.
  • The resource can be found at www.mkarthikeyan.bioinfoau.org/HTNpedia.
  • This initiative aims to enhance the study and management of hypertension.
Abstract

Keywords:
HTNpedia.HypertensionSNPdrug moleculesgenesproteins

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