Reduced left ventricular dynamics modeling based on a cylindrical assumption.

Area of Science:

• Biomedical Engineering
• Computational Mechanics
• Medical Device Development

Background:

• Full-order biomechanical models of the heart are computationally intensive, limiting clinical applications.
• Reduced models are essential for efficient simulations, pre-calibration, and real-time predictions in cardiac mechanics.

Purpose of the Study:

• To develop a reduced biomechanical model of the left ventricle.
• To create a model with reduced geometry and kinematics while retaining physical meaning for variables and parameters.
• To enable accurate representation of myofiber orientation and ventricular twist.

Main Methods:

• Developed a reduced ventricular model using cylindrical geometry and kinematics.
• Incorporated a fully dynamical formulation integrated with an open-loop lumped circulation model.
• Utilized a novel numerical approach with consistent spatial (finite element) and time discretizations.

Main Results:

• The proposed model effectively describes myofiber orientation and contraction patterns like ventricular twist.
• The model demonstrates physiological responses and sensitivity to various numerical and physical parameters.
• The reformulated cylinder closure and novel numerical approach enhance model usability.

Conclusions:

• The reduced biomechanical model offers a computationally efficient and physically meaningful representation of left ventricular mechanics.
• This model facilitates faster predictions and real-time applications in cardiac biomechanics.
• The developed model serves as a valuable tool for advancing next-generation medical technologies.