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Related Experiment Videos

Aquagenic angioedema.

A Parks, C Camisa

    Cutis
    |June 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    A young man experienced lip swelling and itching after swimming, triggered by tap water. Symptoms resolved, indicating water-induced angioedema is a possibility.

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    Area of Science:

    • Dermatology
    • Allergology

    Background:

    • Physical urticaria and angioedema are hypersensitivity reactions to external stimuli.
    • Common triggers include cold, heat, pressure, and sunlight.

    Observation:

    • A 21-year-old male presented with recurrent lip swelling and generalized itching after swimming.
    • Symptoms occurred without visible hives.
    • Provocative testing with tap water induced transient edema and pruritus.

    Findings:

    • Cholinergic urticaria was ruled out through sweating and methacholine challenge tests.
    • The patient's symptoms resolved spontaneously over several weeks.
    • Subsequent tap water exposure and swimming did not elicit a reaction.

    Implications:

    • This case suggests tap water can be a physical agent causing angioedema, and potentially urticaria.
    • Water should be considered alongside other physical agents in the differential diagnosis of inducible hypersensitivity reactions.
    • Further investigation into water-induced hypersensitivity mechanisms is warranted.