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A Reliable and Secure Method for Sharing Genomic Data.

Dinis B Cruz1, João R Almeida1,2, Jorge M Silva1

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|May 19, 2023
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Summary
This summary is machine-generated.

This study introduces a novel tool for securely encrypting and decrypting genomic data (FASTA files). It enhances data sharing by reducing shared keys and combining encryption methods, improving security and usability in genomics.

Keywords:
DNA sequencingFASTA filesGenomicsdata securitydecryptionencryption

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Area of Science:

  • Genomics and Bioinformatics
  • Computational Biology
  • Medical Informatics

Background:

  • Genomics advances medicine, enabling personalized treatments and disease understanding.
  • Secure sharing of sensitive genomic data is essential for research progress.
  • Existing methods for genomic data protection present challenges in security and key management.

Purpose of the Study:

  • To develop a novel tool for secure encryption and decryption of FASTA files.
  • To enable secure genomic data sharing without common secrets and with fewer shared keys.
  • To improve the security and usability of genomic data protection methods.

Main Methods:

  • The proposed tool integrates symmetric encryption (Advanced Encryption Standard - AES) and asymmetric encryption (Rivest-Shamir-Adleman - RSA).
  • It facilitates secure data transfer and storage for genomic datasets.
  • The system is designed for efficient key management between data-sharing pairs.

Main Results:

  • The developed tool provides secure encryption and decryption of FASTA files.
  • It operates without requiring a common secret between users and minimizes shared keys.
  • Performance tests indicate the tool is fast, reliable, and secure, surpassing existing solutions.

Conclusions:

  • The new tool offers a significant advancement for the secure sharing and utilization of sensitive genomic data.
  • Its combination of encryption techniques and simplified key management addresses critical needs in bioinformatics.
  • This facilitates further progress in personalized medicine and genomic research through enhanced data security.