Related Experiment Video
Updated: Jul 30, 2025

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
Published on: March 3, 2023
Multidrug Resistant Escherichia coli among Urinary Samples of Patients with Urinary Tract Infection in the
Raina Chaudhary1, Manoj Pradhan1, Sabita Bhatta1
1Department of Microbiology, Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal.
Introduction:
Urinary Tract Infection one of the most common and manageable infections still holds its position as a major public health issue worldwide due to an increase in the number of multidrug resistant bacteria. This study aims to find out the prevalence of multidrug resistant Escherichia coli among urinary samples of patients with urinary tract infections in the microbiology Department of a tertiary care center.
Methods:
A descriptive cross-sectional study was carried out at a tertiary care centre from 8 August 2018 to 9 January 2019. Ethical approval was received from the Institutional Review Committee (Reference number: 123/2018). Clinically suspected cases of urinary tract infection were included in this study. A convenience sampling method was used. Point estimate and 95% Confidence Interval were calculated.
Results:
Among 594 patients with urinary tract infections, the prevalence of multidrug resistant Escherichia coli was 102 (17.17%) (14.14-20.20, 95% Confidence Interval). Out of which, the production of extended-spectrum beta-lactamase and AmpC beta-lactamase were observed in 74 (72.54%), and 28 (27.45%) isolates respectively. The co-production of extended-spectrum beta-lactamases/AmpC was observed in 17 (16.67%).
Conclusions:
The prevalence of multidrug resistant Escherichia coli among patients urinary samples of patient with urinary tract infection was lower as compared to the other studies done in similar settings.
Keywords:
antibiotics; Escherichia coli; urinary tract infection.
Related Concept Videos
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Urine Studies II: Urine Culture and Sensitivity Test
Urinary Tract Infection I: Introduction
Urinary Tract Infection II: Pathophysiology
Urinary Tract Infection IV: Nursing Management
Acute Pyelonephritis II: Diagnostic Studies and Management

