Related Experiment Video
Updated: Jul 30, 2025

Modeling Spontaneous Metastatic Renal Cell Carcinoma mRCC in Mice Following Nephrectomy
Published on: April 29, 2014
Congenital Mesoblastic Nephroma: A Case Report
Ankita Simkhada1, Ramesh Paudel1, Nisha Sharma1
1Department of Pathology, Maharajgunj Medical Campus, Maharajgunj, Kathmandu, Nepal.
Congenital mesoblastic nephroma is a rare kidney tumor in infants. This case report details a neonate diagnosed with this mixed-subtype tumor after presenting with leg swelling.
Area of Science:
- Pediatric Oncology
- Nephrology
- Pathology
Background:
- Congenital mesoblastic nephroma (CMN) is the most common congenital renal tumor, typically presenting in infancy.
- These rare renal tumors require accurate diagnosis and timely management.
Observation:
- A term female neonate presented with bilateral lower limb swelling within the first week of life.
- Radiological evaluation, including ultrasonography, identified an intra-abdominal mass.
Findings:
- The neonate underwent radical nephroureterectomy for the abdominal mass.
- Histopathological examination confirmed the diagnosis of congenital mesoblastic nephroma, specifically of the mixed subtype.
Implications:
- This case highlights the importance of considering CMN in neonates with abdominal masses and leg swelling.
- Early diagnosis and surgical intervention are crucial for managing congenital mesoblastic nephroma.
- Understanding the mixed subtype is important for prognosis and treatment planning in pediatric kidney neoplasms.
More Related Videos
05:44Author Spotlight: Collecting the Brain and Serum from the Same Mice Fetus to Study Brain Tumor Development
Published on: May 17, 2024
08:57Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
Published on: May 17, 2024