Gastric leiomyoma as an atypical cause of upper gastrointestinal bleeding

We introduce the case of a 40-year-old male with no medical history of interest who was admitted in the Digestive System unit due to upper gastrointestinal bleeding, and a large protruding lesion located in gastric antrum was detected during oral endoscopy, but biopsies were negative for malignancy. Therefore, endoscopic ultrasound was performed, confirming the submucosal origin of the lesion, puncturing it, and obtaining histological results compatible with leiomyoma. Gastric leiomyomas are rare mesenchymal tumors that are usually asymptomatic and are detected by performing a procedure for another reason. The definitive diagnosis is histological, being sometimes difficult to obtain samples given the submucosal origin of these lesions. The main treatment is surgery, although endoscopic resection is accepted in certain cases.