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The Quantra System: System Description and Protocols for Measurements
Oksana Volod1, Francesco Viola2
1Cedars-Sinai Medical Center, Los Angeles, CA, USA. Oksana.Volod@cshs.org.
Methods in Molecular Biology (Clifton, N.J.)
|May 19, 2023
Summary
The new Quantra System uses ultrasound (SEER Sonorheometry) for blood viscoelastic testing, offering improved reproducibility over older cup-and-pin methods like TEG and ROTEM.
Area of Science:
- Hemostasis and thrombosis research
- Medical device technology
- Point-of-care diagnostics
Background:
- Viscoelastic (VET) technologies like TEG 5000 and ROTEM delta have dominated blood analysis for 20 years.
- These legacy systems utilize a "cup and pin" measurement principle.
- There is a need for advanced VET methods offering enhanced performance and usability.
Purpose of the Study:
- To introduce the Quantra System, a novel ultrasound-based viscoelastic testing device.
- To describe the SEER Sonorheometry principle of operation.
- To outline the Quantra's cartridges, clinical applications, and result interpretation.
Main Methods:
- The Quantra System employs ultrasound (SEER Sonorheometry) to assess blood viscoelastic properties.
- It is a cartridge-based, automated system designed for ease of use.
- The device focuses on simplifying specimen handling and improving result consistency.
Main Results:
- The Quantra System represents a new generation of VET technology.
- It offers potential advantages in specimen management and reproducibility compared to legacy devices.
- Detailed descriptions of its operation and interpretation are provided.
Conclusions:
- The Quantra System, utilizing SEER Sonorheometry, is a significant advancement in viscoelastic blood analysis.
- Its automated, cartridge-based design promises improved efficiency and reliability in clinical settings.
- This technology offers a modern alternative to traditional "cup and pin" VET methods.
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