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The Quantra System: System Description and Protocols for Measurements.

Oksana Volod1, Francesco Viola2

  • 1Cedars-Sinai Medical Center, Los Angeles, CA, USA. Oksana.Volod@cshs.org.

Methods in Molecular Biology (Clifton, N.J.)
|May 19, 2023
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Summary
This summary is machine-generated.

The new Quantra System uses ultrasound (SEER Sonorheometry) for blood viscoelastic testing, offering improved reproducibility over older cup-and-pin methods like TEG and ROTEM.

Keywords:
QPlusQStatQuantraSEER SonorheometryViscoelastic testing

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Area of Science:

  • Hemostasis and thrombosis research
  • Medical device technology
  • Point-of-care diagnostics

Background:

  • Viscoelastic (VET) technologies like TEG 5000 and ROTEM delta have dominated blood analysis for 20 years.
  • These legacy systems utilize a "cup and pin" measurement principle.
  • There is a need for advanced VET methods offering enhanced performance and usability.

Purpose of the Study:

  • To introduce the Quantra System, a novel ultrasound-based viscoelastic testing device.
  • To describe the SEER Sonorheometry principle of operation.
  • To outline the Quantra's cartridges, clinical applications, and result interpretation.

Main Methods:

  • The Quantra System employs ultrasound (SEER Sonorheometry) to assess blood viscoelastic properties.
  • It is a cartridge-based, automated system designed for ease of use.
  • The device focuses on simplifying specimen handling and improving result consistency.

Main Results:

  • The Quantra System represents a new generation of VET technology.
  • It offers potential advantages in specimen management and reproducibility compared to legacy devices.
  • Detailed descriptions of its operation and interpretation are provided.

Conclusions:

  • The Quantra System, utilizing SEER Sonorheometry, is a significant advancement in viscoelastic blood analysis.
  • Its automated, cartridge-based design promises improved efficiency and reliability in clinical settings.
  • This technology offers a modern alternative to traditional "cup and pin" VET methods.