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Updated: Jul 29, 2025

Stenosis of the Inferior Vena Cava: A Murine Model of Deep Vein Thrombosis
Published on: December 22, 2017
Inferior Vena Cava Filter Occlusion Causing Phlegmasia Alba Dolens.
Jeremy N Burt1, Joshua D Hirsh1, Ramola M Panchal1
1Department of Surgery, University of Mississippi Medical Center Jackson, MS, USA.
Phlegmasia alba dolens, a rare condition, can stem from iliofemoral vein clots or a blocked inferior vena cava filter. A staged endovascular approach successfully treated acute on chronic caval thrombosis in a patient with a filter.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Thrombosis Management
Background:
- Phlegmasia alba dolens is a rare complication of extensive iliofemoral vein thrombosis.
- Inferior vena cava (IVC) filters, while life-saving, can rarely lead to caval thrombosis.
- This case highlights a unique presentation of phlegmasia alba dolens secondary to a clotted IVC filter.
Purpose of the Study:
- To report a case of phlegmasia alba dolens caused by an occluded IVC filter.
- To illustrate the successful application of a staged endovascular approach for managing acute on chronic caval thrombosis.
- To emphasize the importance of considering IVC filter complications in patients with severe lower extremity venous thrombosis.
Main Methods:
- A 39-year-old patient with protein S deficiency and a history of IVC filter placement presented with severe bilateral leg pain and swelling.
- Diagnostic workup included venous duplex and venography, revealing extensive deep vein thromboses and infrarenal IVC occlusion at the filter.
- Treatment involved IVC filter retrieval, endovascular thrombectomy, and venoplasty.
Main Results:
- The patient presented with extensive bilateral deep vein thromboses extending from the external iliac to the popliteal veins.
- Venography confirmed infrarenal IVC occlusion at the level of the IVC filter.
- Following endovascular intervention and filter removal, the patient showed significant clinical improvement and was discharged on anticoagulation.
Conclusions:
- A staged endovascular approach can be effective for treating acute on chronic caval thrombosis associated with IVC filters.
- Prompt diagnosis and intervention are crucial for managing phlegmasia alba dolens secondary to IVC filter complications.
- This case underscores the potential for endovascular techniques to resolve complex caval thrombotic events.
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