Related Experiment Videos
Ketoconazole treatment in superficial mycoses
Drugs Under Experimental and Clinical Research
|January 1, 1986
Summary
Ketoconazole, a broad-spectrum antifungal imidazole drug, shows efficacy in treating various superficial and deep fungal infections like candidosis and pityriasis versicolor. Clinical trials indicate successful administration with no significant adverse haematochemical effects observed.
Area of Science:
- Mycology
- Pharmacology
- Dermatology
Background:
- Ketoconazole represents a novel imidazole-derivative antifungal agent.
- It exhibits broad-spectrum activity against superficial and deep fungal pathogens.
Purpose of the Study:
- To evaluate the clinical efficacy and safety of oral ketoconazole.
- To assess its utility in treating diverse mycotic diseases.
Main Methods:
- Administration of oral ketoconazole for treatment of various fungal infections.
- Clinical observation and case reporting from multiple research centers.
Main Results:
- Successful treatment outcomes reported for dermatophytosis, candidosis, and pityriasis versicolor.
- Efficacy in tinea corporis, tinea cruris, tinea pedis, and certain Candida infections (onychomycosis, intertrigo, mucocutaneous).
- No significant adverse haematochemical changes noted post-treatment.
Conclusions:
- Oral ketoconazole is an effective therapeutic option for a range of fungal infections.
- The drug demonstrates a favorable safety profile with minimal observed side effects.