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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
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'Microincisional trabeculectomy for glaucoma".

Aparna Rao1, Sardar Khan1, Sujoy Mukherjee1

  • 1Glaucoma Service, LV Prasad Eye Institute, Patia, Bhubaneswar, India.

Plos One
|May 19, 2023
PubMed
Summary
This summary is machine-generated.

Microincisional trabeculectomy (MIT) effectively lowers intraocular pressure and reduces medication needs in open-angle glaucoma patients. This ab-interno technique shows promising short-term outcomes with minimal complications.

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Area of Science:

  • Ophthalmology
  • Glaucoma Surgery
  • Minimally Invasive Procedures

Background:

  • Open-angle glaucoma (OAG) management often requires surgical intervention to control intraocular pressure (IOP).
  • Traditional trabeculectomy can be associated with significant complications.
  • Microincisional trabeculectomy (MIT) offers a less invasive surgical approach.

Purpose of the Study:

  • To evaluate the short-term clinical outcomes of microincisional trabeculectomy (MIT).
  • To assess the efficacy of MIT as an ab-interno trabeculectomy technique.
  • To analyze IOP reduction and medication requirements post-MIT.

Main Methods:

  • A prospective study included 32 eyes of patients with OAG undergoing MIT between September 2021 and June 2022.
  • MIT was performed ab-interno using microscissors and microforceps.
  • Outcomes measured included IOP reduction, medication use, surgical success rates, and complications at 6 months.

Main Results:

  • All 32 eyes achieved >30% IOP reduction, with a mean final IOP of 14±6.9 mm Hg at 6 months.
  • Surgical success was observed in 31 of 32 eyes, with 28 achieving complete success (no more than one medication).
  • Complications were limited to transient hyphema and IOP spikes, with no additional interventions required for most cases.

Conclusions:

  • Microincisional trabeculectomy (MIT) is an effective ab-interno technique for short-term IOP control in OAG.
  • MIT demonstrates a favorable safety profile with fewer complications compared to traditional methods.
  • Further long-term studies are needed to compare MIT with other glaucoma surgical procedures.