Celiac Plexus Block to Treat Refractory Feed Induced Dystonia in Children with Severe Neurodisability: A Single Center Case Series
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David I Campbell1, Rosalind M Rabone1, Ala Fadilah1
1From the Sheffield Children's Hospital NHS Foundation Trust UK, Sheffield, United Kingdom.
Insights
Celiac plexus blockade (CPB) offers a safe and effective treatment for children with severe neurodisability experiencing feed intolerance or feed-induced dystonia (FID) when other therapies fail.
Area of Science:
- Pediatric Gastroenterology
- Interventional Radiology
- Pain Management
Background:
- Children with severe neurodisability often suffer from refractory feed intolerance, pain, or dystonia.
- The neuroenteric system is significantly impacted by feeding issues in this population.
- Existing therapies may be insufficient for managing these complex conditions.
Purpose of the Study:
- To describe the procedure, safety, and outcomes of celiac plexus blockade (CPB) in children with neurodisability and feeding problems.
- To evaluate CPB as a treatment for feed-induced dystonia (FID) and refractory feed intolerance.
- To review the pathophysiological response to feeding in neurodisabled children.
Main Methods:
- A 2-stage CT-guided temporary celiac plexus blockade followed by neurolysis technique was employed.
- A case series of 5 pediatric patients with life-limiting conditions and significant disability was compiled.
- The study involved 10 separate procedures in the 5 children.
Main Results:
- Celiac plexus blockade (CPB) demonstrated positive outcomes in 3 out of 4 cases of pediatric feed-induced dystonia (FID).
- Two of three patients on parenteral nutrition showed improved feed tolerance post-procedure.
- All pediatric patients tolerated the procedure well, with no documented post-procedure complications.
Conclusions:
- Celiac plexus blockade (CPB) is a safe treatment option for selected pediatric cases.
- CPB can effectively manage life-threatening feed-induced dystonia or intestinal failure when other treatments have failed.
- This interventional technique offers a viable solution for refractory feeding issues in neurodisabled children.
Abstract:
This observational study describes the procedure technique, safety outcomes, and patient responses to celiac plexus blockade (CPB) in children with severe neurodisability with refractory feed intolerance, feed induced pain or feed induced dystonia (FID).
Method:
A review of the pathophysiological response to feeding in children with significant neurodisability and the effect on the neuroenteric system. A 2-stage CT-guided temporary celiac plexus blockade followed by neurolysis technique is described. We compile a case series of 5 patients with life limiting conditions and significant disability undergoing CPB in a single tertiary pediatric hospital.
Results:
A total of 10 separate procedures in 5 children were completed. A positive outcome was observed in 3 out of 4 cases of pediatric FID. Two of the three patients on parenteral nutrition had improved feed tolerance postprocedure. All children tolerated the procedure well, no postprocedure complications were documented.
Conclusions:
In selected cases, children with life-threatening feed induced dystonia or effective intestinal failure can be safely treated with celiac plexus blockade when other therapies have failed.
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