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Updated: Jul 29, 2025

Endoscopic Cholesteatoma Surgery
Published on: January 19, 2022
Fungal otitis externa and tympanic membrane perforation
Gur Paramjeet Singh Gill1, Vineet Panchal2, Rupinder Bakshi3
1NC Medical College, Panipat, India.
Clotrimazole solution is a safe treatment for otomycosis (fungal ear infections) with tympanic membrane perforation. This study found no significant differences between patched and non-patched groups in managing this common ear condition.
Area of Science:
- Otolaryngology
- Mycology
- Infectious Diseases
Background:
- Otomycosis is a common fungal infection of the external auditory canal, prevalent in warm, humid climates.
- Increased antibiotic eardrop use and factors like swimming and immunocompromised states contribute to rising otomycosis cases.
- Risk factors include diabetes mellitus, AIDS, pregnancy, post-mastoidectomy, tympanic membrane perforation, hearing aid use, and self-inflicted injuries.
Purpose of the Study:
- To evaluate the safety and efficacy of clotrimazole solution in managing otomycosis with central tympanic membrane perforation.
- To compare outcomes between a patched group and a non-patched group receiving clotrimazole treatment.
Main Methods:
- A study involving 40 patients with otomycosis and tympanic membrane perforation was conducted between August and September 2021.
- Diagnosis was based on physical findings like whitish ear discharge and presence of hyphae in the external auditory canal, ear drum, and middle ear mucosa.
- Patients were divided into patched and non-patched groups, with follow-up at 3 weeks.
Main Results:
- A total of 40 patients were included, with 20 in the patched group and 20 in the non-patched group.
- No significant statistical variations were observed between the groups regarding age, perforation size, mycological analysis, or pure tone audiometry.
- Data was analyzed for patients who completed the 3-week follow-up.
Conclusions:
- Clotrimazole solution is a safe and effective treatment for otomycosis in patients with tympanic membrane perforation.
- Otolaryngologists routinely diagnose otomycosis through medical examination.
- Increased humidity can lead to fungal overgrowth in the external auditory canal, causing acute otomycosis.
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