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Antibiotic use and multiple sclerosis: A systematic review and meta-analysis
Ali Hosseinzadeh1, Sohrab Iranpour2, Hossein Ali Adineh3
1Department of Epidemiology, School of Public Health, Shahroud University of Medical Sciences, Shahroud, Iran.
Multiple Sclerosis and Related Disorders
|May 20, 2023
Summary
This review found no significant link between antibiotic use and multiple sclerosis (MS) risk. Further research is needed to confirm these findings on antibiotic and penicillin use and MS.
Area of Science:
- Neurology
- Epidemiology
- Pharmacology
Background:
- Conflicting epidemiological data exists regarding antibiotic use and multiple sclerosis (MS) risk.
- A systematic review and meta-analysis were performed to clarify the association between antibiotic exposure and MS.
- Understanding this relationship is crucial for public health and clinical practice.
Conclusions:
- This meta-analysis did not establish a significant association between antibiotic or penicillin use and the risk of multiple sclerosis.
- The study highlights significant heterogeneity among the included studies.
- Further high-quality, well-designed research is warranted to definitively ascertain the relationship between antibiotic exposure and MS risk.
