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Updated: Jul 29, 2025

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
Published on: August 9, 2024
Initial development of the chest pain conception questionnaire
John R Blakeman1, Ann L Eckhardt2, MyoungJin Kim3
1Assistant Professor, Mennonite College of Nursing, Illinois State University, Campus Box 5810, Normal, IL 1790-5810, United States.
Insights
Researchers developed the Chest Pain Conception Questionnaire (CPCQ) to understand public perceptions of chest pain related to acute coronary syndrome (ACS). This validated instrument helps assess how people understand this critical heart attack symptom.
Area of Science:
- Cardiology
- Psychometrics
- Health Communication
Background:
- Chest pain is a recognized symptom of acute coronary syndrome (ACS), yet public understanding of this symptom is poorly understood.
- Lay public conceptions of chest pain related to ACS require further investigation.
Purpose of the Study:
- To develop and validate an instrument measuring the lay public's conceptions of chest pain associated with ACS.
- The Chest Pain Conception Questionnaire (CPCQ) was created to address this knowledge gap.
Main Methods:
- Instrument development involved the Theory of Unpleasant Symptoms and literature review.
- Expert feedback and two rounds of pilot testing with the target population were utilized.
- Psychometric testing, including exploratory factor analysis, was conducted to establish validity.
Main Results:
- The final CPCQ instrument includes 23 items (open-ended, Likert-type, and multiple-choice) written at a 7th-grade reading level.
- High content validity (scale-level index of 0.99) and construct validity were supported by exploratory factor analysis.
Conclusions:
- The study provides preliminary evidence for the validity of the Chest Pain Conception Questionnaire (CPCQ).
- The CPCQ is a valuable tool for assessing public understanding of chest pain as an ACS symptom.
Background:
Even though "chest pain" is often highlighted as a key heart attack symptom for which individuals should seek care, little is known about the ways that the lay public conceives of chest pain related to acute coronary syndrome (ACS).
Objectives:
The purpose of this four-step process was to develop an instrument to measure the lay public's conceptions of chest pain related to ACS.
Methods:
The Chest Pain Conception Questionnaire (CPCQ) was drafted based on the Theory of Unpleasant Symptoms and findings from the published literature. We then leveraged two rounds of expert feedback to calculate item-level and scale-level content validity indices. Two rounds of pilot testing (N = 51 and N = 300) were conducted with members of the target population. Psychometric testing was also conducted, including exploratory factor analysis.
Results:
The multi-step development process resulted in an instrument that is comprised of 23 items (2 open-ended questions, 13 short scenarios with Likert-type ratings, and 8 multiple-choice questions) and written at a 7th grade level. The scale-level content validity index was 0.99. Exploratory factor analysis findings also supported construct validity.
Conclusions:
This paper provides preliminary evidence of the CPCQ's validity.
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