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Related Experiment Video

Updated: Jul 29, 2025

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

[Intraoperative Visual Evoked Potential].

Takakazu Kawamata¹

¹Department of Neurosurgery, Tokyo Women's Medical University.

No Shinkei Geka. Neurological Surgery

|May 22, 2023

Summary

Intraoperative visual evoked potential (VEP) monitoring, with simultaneous electroretinogram (ERG), helps prevent vision loss during skull base surgeries. A 50% VEP amplitude reduction signals critical risk, prompting surgical adjustment to preserve visual function.

Area of Science:

Neurosurgery
Neurophysiology
Ophthalmology

Context:

Anterior skull base and parasellar tumors can affect optic pathways, risking visual complications.
Intraoperative visual evoked potential (VEP) monitoring is emerging for managing these risks.
Simultaneous electroretinogram (ERG) recording aids in excluding technical errors.

Purpose:

To evaluate the utility of intraoperative VEP monitoring in preventing postoperative visual complications.
To define critical parameters for VEP monitoring, such as amplitude reduction.
To understand the limitations of current intraoperative VEP systems.

Summary:

Intraoperative VEP, defined by P100 and N75 waves, monitors optic pathway function during surgery.
Reproducibility is key, especially with pre-existing visual impairment or diminished intraoperative amplitude.

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A 50% amplitude reduction necessitates considering surgical modification.

Impact:

Intraoperative VEP with ERG provides a real-time warning system for surgeons.
It guides surgical manipulation to minimize the risk of postoperative visual impairment.
Understanding VEP principles and limitations is crucial for effective utilization.