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Demonstrating proof of concept for value-based agreements in Europe: two real-world cases
Elizabeth A Griffiths1, Onivefu E Odelade1, Joana Gostkorzewicz2
1AstraZeneca, Cambridge, UK.
Summary
Value-based agreements (VBAs) link medicine cost to real-world outcomes, improving patient access and reducing payer uncertainty. Successful implementation requires stakeholder engagement and robust data systems.
Area of Science:
- Health economics
- Pharmaceutical policy
- Real-world evidence
Background:
- Value-based agreements (VBAs) link medicine access, reimbursement, or price to real-world usage and impact.
- VBAs aim to enhance patient outcomes and generate savings while mitigating payer risk and uncertainty.
Purpose of the Study:
- To outline key challenges, enablers, and a framework for successful VBA implementation.
- To increase confidence in the future use of VBAs by comparing two case studies.
Main Methods:
- Commentary based on the experience of two VBAs for AstraZeneca medicines.
- Analysis of factors contributing to successful negotiation and implementation.
Main Results:
- Successful VBA negotiation requires engagement from payers, manufacturers, physicians, and institutions.
- Robust, accessible, and user-friendly data collection systems are crucial.
- A supportive legal/policy framework facilitates innovative contracting.
Conclusions:
- The analyzed VBAs demonstrate proof of concept for implementation across different healthcare settings.
- These findings can inform the design and execution of future value-based agreements.
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