Evaluation of mixture toxicity literature and chemical space: a data centric approach
Vatsal Mehta1, Mahmoud Shobair1, Catherine Mahony2
1The Procter & Gamble Company, Cincinnati, OH, USA.
Abstract:
Using the Abstract Sifter tool to analyse PubMed, we reveal published mixture related research most commonly relates to water pollutants, pesticides, environmental pollutants, insecticides, soil pollutants, and chemicals described as persistent, bioaccumulative, and toxic. Furthermore, we discern individual chemicals that also identify as priority chemicals in biomonitoring initiatives and using an ontology-based chemical classification, at the level of the chemical subclass, found these priority chemicals overlap with just 9% of the REACH chemical space.
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