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High-throughput Detection Method for Influenza Virus
Published on: February 4, 2012
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Mpox virus Clade IIb detection in the air
1National Food Safety Authority (NFSA), Aswan Branch, Aswan, Egypt.
Journal of Medical Virology
|May 22, 2023
Summary
Mpox virus (formerly monkeypox) can spread asymptomatically. Recent reviews show mpox virus DNA in air samples, highlighting the need for further research on transmission routes and healthcare facility risks.
Area of Science:
- Virology
- Epidemiology
- Public Health
Background:
- Mpox is a viral zoonotic disease endemic to Africa, caused by the Mpox virus (Orthopoxvirus genus).
- The 2022 mpox outbreak spread globally, with potential transmission from asymptomatic or paucisymptomatic individuals.
- Two major genetic clades exist: Clade I (Central African) and Clade II (West African).
Purpose of the Study:
- To review recent evidence on Mpox virus detection in environmental air samples.
- To highlight the need for further research on mpox transmission dynamics and risks in healthcare settings.
Main Methods:
- Review of recent scientific literature and evidence.
- Analysis of mpox virus detection in air samples from patient environments during the 2022 outbreak.
Main Results:
- Mpox virus (Clade IIb) DNA was detected in air samples from patient environments.
- Asymptomatic or paucisymptomatic transmission is a suspected factor in mpox spread.
- Standard PCR testing cannot distinguish infectious mpox viruses; virus culture is recommended.
Conclusions:
- Further research is required to assess the risk of airborne mpox virus DNA to immunocompromised patients in healthcare facilities.
- Epidemiological studies, particularly in Africa, are crucial for understanding mpox transmission.
- Enhanced surveillance and diagnostic methods are needed to control mpox outbreaks.
