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Updated: Jul 29, 2025
Assaying for Inorganic Polyphosphate in Bacteria
Published on: January 21, 2019
A ratiometric, colorimetric fluorescent probe with a large emission shift for the rapid detection of diethyl
Xue-Shuang Yu1, Rui Zuo1, Ming-Ye Shuai1
1School of Chemistry & School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, People's Republic of China. pengyu@swjtu.edu.edu.cn.
Abstract:
A new ratiometric and colorimetric probe (SWJT-16) based on the isophorone skeleton to detect diethyl chlorophosphite (DCP), a nerve agent mimic, was designed and synthesized. SWJT-16 underwent a nucleophilic substitution reaction with DCP in DMF, leading to a large emission shift (Δλem = 174 nm) accompanied by a significant color change from blue to yellow under visible light. All these changes occurred within 6 seconds, faster than those of most reported ratiometric fluorescent probes for DCP. Furthermore, SWJT-16 was successfully employed to monitor gaseous DCP.
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