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Updated: Jul 29, 2025

Tissue Characterization after a New Disaggregation Method for Skin Micro-Grafts Generation
Published on: March 4, 2016
Cultured Skin Autograft in Subtotal Pediatric Scalp Avulsion
Michael S Powell1, Tamara Osborn, Sagar T Mehta
1At University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA, Michael S. Powell, MBA, is Medical Student, College of Medicine; Tamara Osborn, MD, is Resident, Department of General Surgery; and Sagar T. Mehta, MD, is Assistant Professor, Division of Plastic and Reconstructive Surgery.
Abstract:
Pediatric scalp avulsions represent a reconstructive challenge because of the unique features of scalp tissue. When microsurgical reimplantation is not feasible, alternative approaches such as skin grafting, free flap transfer with latissimus flap, or tissue expansion are considered. Generally, there is no consensus regarding management of this trauma, and, oftentimes, multiple reconstructive techniques may be needed for definitive coverage. This case study describes the reconstruction of a pediatric subtotal scalp avulsion using a dermal regeneration template and novel autologous homologous skin construct. This case was complicated by the absence of original tissue for reimplantation, excessive size of the defect relative to body habitus, and family concerns for future hair-bearing function. The reconstruction successfully provided definitive coverage and significantly reduced the size of the donor site and associated compilations. However, the hair-bearing potential of the tissue has yet to be determined.

