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Recent Advances in Imported Malaria Pathogenesis, Diagnosis, and Management
1Cleveland, OH USA Department of Medicine, Case Western Reserve University/University Hospitals Cleveland Medical Center.
Current Emergency and Hospital Medicine Reports
|May 22, 2023
Summary
Malaria diagnosis and treatment are crucial for travelers returning from endemic areas. Prompt recognition and management of malaria, caused by Plasmodium parasites, can prevent severe outcomes.
Area of Science:
- * Tropical medicine and infectious diseases.
- * Parasitology and global health.
Background:
- * Malaria is a significant parasitic disease prevalent in tropical and subtropical regions.
- * It affects local populations and international travelers.
- * Recent progress in malaria control is threatened by drug resistance and global health disruptions.
Purpose of the Study:
- * To offer clinicians in non-endemic areas a detailed review of malaria.
- * To cover the latest data on Plasmodium parasites, clinical presentations, diagnostics, and treatments.
Main Methods:
- * Comprehensive literature review of recent data on malaria.
- * Focus on microbiologic and pathophysiologic aspects.
- * Analysis of clinical presentations, diagnostic tools, and therapeutic strategies.
Main Results:
- * Five Plasmodium species cause malaria, with varying clinical and pathological features.
- * Early diagnosis using microscopy and rapid diagnostic tests is vital.
- * Artemisinin-based combination therapy is the recommended treatment.
Conclusions:
- * Clinicians in non-endemic regions must consider malaria in febrile travelers.
- * Timely diagnosis and guideline-directed treatment are essential to improve outcomes.
- * Delays in malaria management can lead to severe complications.
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