Related Experiment Video
Updated: Jul 29, 2025

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
A sharp interface Lagrangian-Eulerian method for flexible-body fluid-structure interaction.
Ebrahim M Kolahdouz1, David R Wells2, Simone Rossi2
1Center for Computational Biology, Flatiron Institute, Simons Foundation, New York, NY, USA.
This study presents a new immersed Lagrangian-Eulerian (ILE) method for simulating fluid-structure interaction (FSI) with flexible bodies. The flexible-body immersed Lagrangian-Eulerian (ILE) approach accurately models complex FSI phenomena, including blood clot transport.
Area of Science:
- Computational fluid dynamics
- Solid mechanics
- Fluid-structure interaction (FSI)
Background:
- Simulating fluid-structure interaction (FSI) with flexible bodies presents challenges, especially with nonlinear material models and varying mass density ratios.
- Existing immersed boundary (IB) methods often lack the accuracy of body-fitted approaches in resolving stresses at the fluid-structure interface.
Purpose of the Study:
- To introduce a novel sharp-interface immersed Lagrangian-Eulerian (ILE) scheme for simulating FSI with flexible bodies.
- To extend previous work on rigid-body FSI to accommodate general nonlinear material models and a wide range of mass density ratios.
Main Methods:
- The flexible-body ILE scheme combines the geometric flexibility of IB methods with accurate interface stress resolution.
- Distinct momentum equations for fluid and solid subregions are coupled using a Dirichlet-Neumann strategy.
- An immersed interface method (IIM) is employed for stress jump conditions, enabling efficient structured-grid solvers for incompressible Navier-Stokes equations.
- Finite element analysis is used for large-deformation nonlinear elasticity of the solid structures.
Main Results:
- The ILE formulation achieves accuracy comparable to body-fitted methods while maintaining the flexibility of IB approaches.
- The penalty approach with distinct interface representations simplifies linear solvers and enables multi-rate time stepping.
- Grid convergence studies demonstrate second-order accuracy in volume conservation and interface discrepancies, and first/second-order accuracy in structural displacements.
- Validation against FSI benchmarks and application to blood clot transport in an inferior vena cava filter showcase the method's robustness and accuracy.
Conclusions:
- The developed flexible-body ILE scheme provides a robust and accurate approach for simulating complex FSI problems.
- The method's ability to handle nonlinear materials, diverse density ratios, and realistic scenarios like blood clot transport highlights its broad applicability.
- This sharp-interface approach offers a powerful tool for advancing research in various fields involving fluid-structure interactions.
Related Concept Videos
Eulerian and Lagrangian Flow Descriptions
The Eulerian method focuses on fixed points in space where fluid properties, such as velocity, pressure, and temperature, are observed as the fluid moves between these...
Newtonian Fluid: Problem Solving
A velocity gradient forms within the fluid when a Newtonian fluid is placed between two parallel plates, with...
Fluid Pressure over Curved Plate of Constant Width
Hydrostatic Pressure Force on a Curved Surface
Accelerating Fluids
The motion of the liquid within this infinitesimal cylinder is considered to obtain the pressure difference. Three vertical forces act on this liquid:
Angular Momentum: Rigid Body
This calculation can get complicated when tiny particles within the rigid body are not rotating in the same plane but have...

