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Optimizing Photoneuromodulation Techniques to Evaluate the Role of Green Light-Emitting Diodes in Pain Management
Published on: March 28, 2025
491
[Pain after panretinal photocoagulation: 50-millisecond pulse versus conventional pulse]
Brenda Cortez-Trejo1, María Del Pilar Paz-Sosa1, Álvaro José Montiel-Jarquín2
1Instituto Mexicano del Seguro Social, Centro Médico Nacional "Manuel Ávila Camacho", Hospital de Especialidades de Puebla, Servicio de Oftalmología. Puebla, Puebla, México.
Summary
Panretinal photocoagulation (PRP) using a 50-millisecond pulse significantly reduces patient pain compared to the standard 200-millisecond pulse. This shorter pulse duration offers a more comfortable treatment option for diabetic retinopathy patients.
Area of Science:
- Ophthalmology
- Diabetology
Context:
- Diabetic retinopathy is a leading cause of vision loss, necessitating effective treatments.
- Panretinal photocoagulation (PRP) is a standard treatment for diabetic retinopathy, but can be associated with patient discomfort.
Purpose:
- To compare the level of pain experienced by patients undergoing panretinal photocoagulation (PRP) with a 50-millisecond pulse versus a conventional 200-millisecond pulse.
Summary:
- A comparative, cross-sectional study involving 26 patients found that PRP with a 50-millisecond pulse resulted in a significantly lower mean pain score (3.1) compared to the 200-millisecond pulse (7.5).
- The study utilized the Mann-Whitney U test to analyze pain levels, with a statistically significant difference (p < 0.001) observed between the two groups.
- No complications were reported in either treatment group.
Impact:
- Shorter pulse durations (50 ms) in PRP may offer a less painful and equally safe alternative for managing diabetic retinopathy.
- Findings suggest a potential improvement in patient tolerance and adherence to PRP treatment.

