Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Model Approaches for Pharmacokinetic Data: Physiological Models01:15

Model Approaches for Pharmacokinetic Data: Physiological Models

80
Physiological models in pharmacokinetics are instrumental in understanding the distribution and elimination of drugs within the body. These models describe the drug concentration within target organs, influenced by factors such as drug uptake, tissue volume, and blood flow. Drug uptake is governed by the partition coefficient, which signifies the drug concentration ratio in tissue to that in the blood. The blood flow rate to a specific tissue is expressed as Qt, and the rate of change in tissue...
80
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving01:29

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

88
Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
88
Pharmacokinetic Models: Comparison and Selection Criterion01:26

Pharmacokinetic Models: Comparison and Selection Criterion

114
Physiological and compartmental models are valuable tools used in studying biological systems. These models rely on differential equations to maintain mass balance within the system, ensuring an accurate representation of the dynamic processes at play.
Physiological models take a detailed approach by considering specific molecular processes. They can predict drug distribution, metabolism, and elimination changes, providing a comprehensive understanding of how drugs interact with the body.
114

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A gender-emotion interaction multi-task network for depression recognition via transformer-based multimodal fusion.

Frontiers in psychiatry·2026
Same author

Early proteomic and metabolic signatures of liver and eye in OAT-deficient mice.

Experimental eye research·2026
Same author

Unraveling the intricate link: gut microbiota and recurrent spontaneous abortion.

Frontiers in reproductive health·2026
Same author

Second victim experiences and perceived support among newly registered nurses following patient safety incidents: a cross-sectional study.

Frontiers in public health·2026
Same author

Antibody-Drug Conjugates for Locally Advanced and Metastatic Urothelial Carcinoma: A Systematic Review and Meta-Analysis.

JAMA network open·2026
Same author

Changes in knowledge and attitude after community-based first-aid training: a prospective study with a 12-month follow-up.

World journal of emergency medicine·2026

Related Experiment Video

Updated: Jul 29, 2025

Author Spotlight: Development of an Automated Camera-Based System for Real-Time Blast Overpressure Monitoring and TBI Risk Assessment in Military Training
06:20

Author Spotlight: Development of an Automated Camera-Based System for Real-Time Blast Overpressure Monitoring and TBI Risk Assessment in Military Training

Published on: December 6, 2024

2.9K

A Numerical Modelling Framework for Investigating the Ballistic Performance of Bio-Inspired Body Armours.

Abdallah Ghazlan1, Tuan Ngo1, Ping Tan2

  • 1Department of Infrastructure Engineering, Faculty of Engineering and Information Technology, University of Melbourne, Parkville, VIC 3052, Australia.

Biomimetics (Basel, Switzerland)
|May 23, 2023
PubMed
Summary

Biological structures like nacre and fish scales offer superior ballistic protection. Biomimetic panels inspired by nature demonstrate enhanced multi-hit resistance compared to traditional monolithic materials.

Keywords:
ballistic protectionbio-inspiredbody armourconchcrustaceanfish scalenacre

More Related Videos

Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion
09:32

Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion

Published on: April 11, 2018

9.8K
A Coupled Experiment-finite Element Modeling Methodology for Assessing High Strain Rate Mechanical Response of Soft Biomaterials
11:28

A Coupled Experiment-finite Element Modeling Methodology for Assessing High Strain Rate Mechanical Response of Soft Biomaterials

Published on: May 18, 2015

12.6K

Related Experiment Videos

Last Updated: Jul 29, 2025

Author Spotlight: Development of an Automated Camera-Based System for Real-Time Blast Overpressure Monitoring and TBI Risk Assessment in Military Training
06:20

Author Spotlight: Development of an Automated Camera-Based System for Real-Time Blast Overpressure Monitoring and TBI Risk Assessment in Military Training

Published on: December 6, 2024

2.9K
Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion
09:32

Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion

Published on: April 11, 2018

9.8K
A Coupled Experiment-finite Element Modeling Methodology for Assessing High Strain Rate Mechanical Response of Soft Biomaterials
11:28

A Coupled Experiment-finite Element Modeling Methodology for Assessing High Strain Rate Mechanical Response of Soft Biomaterials

Published on: May 18, 2015

12.6K

Area of Science:

  • Materials Science
  • Biomimetics
  • Ballistic Protection

Background:

  • Biological structures exhibit remarkable damage tolerance, making them ideal models for advanced protective materials.
  • Existing ballistic protection often relies on monolithic materials with limitations in multi-hit resistance.

Purpose of the Study:

  • To develop a finite element modeling framework for evaluating biological structures in ballistic protection.
  • To investigate the projectile impact performance of nacre, conch, fish scales, and crustacean exoskeletons.
  • To compare the efficacy of bio-inspired panels against monolithic panels.

Main Methods:

  • Utilized a finite element modeling framework to simulate projectile impacts on biological structures.
  • Determined optimal geometric parameters for bio-inspired structures to withstand impact.
  • Benchmarked performance against a 4.5 mm thick monolithic panel under identical impact conditions.

Main Results:

  • Biomimetic panels demonstrated superior multi-hit resistant capabilities compared to the monolithic panel.
  • Certain bio-inspired configurations successfully arrested fragment-simulating projectiles at 500 m/s.
  • Performance of some biomimetic designs approached that of the monolithic panel.

Conclusions:

  • Nature-inspired designs offer a promising avenue for developing advanced ballistic protection materials.
  • Bio-inspired panels exhibit enhanced resilience, particularly in multi-hit scenarios.
  • Further research into optimizing biomimetic structures can lead to next-generation protective solutions.