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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
Wise Pattern versus Transverse Pattern Mastectomy in Two-Stage Implant-Based Breast Reconstruction: A Propensity
Joseph M Escandón1, James A Butterfield1, Jose G Christiano1
1From the Division of Plastic and Reconstructive Surgery, Strong Memorial Hospital, University of Rochester Medical Center.
This study compared two incision patterns used in two-stage implant-based breast reconstruction: the Wise pattern and the transverse pattern. Researchers looked at how long it took to exchange tissue expanders, when postmastectomy radiotherapy could begin, and the rate of wound complications. They analyzed records of 393 reconstructions in 239 patients. Before matching, the Wise pattern group had higher rates of wound complications. After adjusting for differences between patients, the Wise pattern still had a higher 30-day wound complication rate. The study found no significant difference in time to exchange expanders or start radiotherapy. The authors concluded that the Wise pattern incision is linked to more wound complications and suggested that delaying tissue expander placement might improve outcomes.
Area of Science:
- Breast reconstruction surgery
- Plastic and reconstructive surgery outcomes research
Background:
Breast reconstruction techniques continue to evolve to address patient-specific anatomical challenges. Surgeons often face decisions about incision patterns that influence postoperative outcomes. Prior research has shown that incision design can affect healing and complication rates. However, no prior work had resolved the comparative safety of the Wise pattern versus the transverse pattern in two-stage implant-based breast reconstruction. This gap motivated a detailed evaluation of complication rates and procedural timing. The need for evidence-based guidance on incision selection remains unmet. Surgeons require data on how different incision patterns influence recovery. Understanding these differences can help optimize patient care. This study addresses a critical need in reconstructive surgery practice.
Purpose Of The Study:
This study aimed to compare wound complication rates and procedural timing between two incision patterns in two-stage implant-based breast reconstruction. The specific problem is the lack of clarity on which incision pattern leads to better outcomes. The authors sought to determine if the Wise pattern incision increases the risk of complications compared to the transverse pattern. They focused on time to initiate radiotherapy and tissue expander exchange. The motivation stems from the need to improve postoperative safety and recovery. Surgeons require evidence to guide incision choices for large or ptotic breasts. This study fills a gap in reconstructive surgery literature. The findings may influence clinical decision-making in breast reconstruction.
Main Methods:
The researchers conducted a retrospective review of patient records from 2011 to 2020. They analyzed 393 two-stage implant-based breast reconstructions across 239 patients. Patients were divided into two groups based on incision pattern. The first group used the Wise pattern, and the second used the transverse pattern. Propensity score matching was applied to reduce confounding variables. The study measured time to tissue expander exchange and time to initiate radiotherapy. Wound-related complications were evaluated within 30 days post-surgery. Statistical analysis compared outcomes between the two groups.
Main Results:
The study found no significant difference in expansion time between the two groups. Time to exchange tissue expanders was also similar (154 days versus 175 days, P = 0.547). Time to initiate postmastectomy radiotherapy did not differ significantly (144 days versus 126 days, P = 0.616). Before matching, the Wise pattern group had a 32% 30-day wound complication rate compared to 10% in the transverse group. The rate of wound complications requiring excision or débridement was 20% in the Wise group versus 7% in the transverse group. After propensity score matching, the Wise pattern still had a higher 30-day wound complication rate (25% versus 10%, P = 0.03). The Wise pattern was independently associated with increased wound complications. These findings suggest a higher risk with the Wise pattern incision.
Conclusions:
The authors concluded that the Wise pattern incision is independently linked to higher wound complication rates. Their findings suggest that the transverse pattern may offer a safer alternative in two-stage implant-based breast reconstruction. The study supports the use of transverse incisions for patients at higher risk of wound issues. Surgeons should consider this when selecting incision patterns. The results do not suggest that the Wise pattern is unsafe but highlight its higher complication risk. The authors propose that delayed tissue expander placement may reduce complications. This conclusion is based on the observed outcomes in the matched cohorts. The study provides evidence to guide incision selection in reconstructive surgery.
Frequently Asked Questions
The study found that the Wise pattern incision is independently associated with a higher 30-day wound complication rate compared to the transverse pattern.
The researchers used a retrospective review and propensity score matching to compare outcomes between the two incision patterns.
The 30-day rate is a standard metric for early postoperative complications and indicates the immediate safety of the surgical approach.
The authors suggest that delayed tissue expander placement may improve the safety profile of the Wise pattern incision.
The time to initiate radiotherapy was 144 days in the Wise pattern group and 126 days in the transverse pattern group.
The authors propose that delayed tissue expander placement may help reduce the complication rate in the Wise pattern group.

