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Updated: Jul 29, 2025

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
Giant cell arteritis presenting with unilateral sixth nerve palsy.
Matthew Colquhoun1, Javier Alegre Abarrategui2, Muhammad Ibrahim Shahzad3
1Rheumatology, Imperial College Healthcare NHS Trust, London, UK matthew.colquhoun@nhs.net.
Giant cell arteritis (GCA), a rare cause of sixth nerve palsy, can be missed if not suspected. Prompt diagnosis and high-dose oral prednisolone treatment led to symptom resolution in a patient with confirmed GCA.
Area of Science:
- Neurology
- Rheumatology
- Ophthalmology
Background:
- Giant cell arteritis (GCA) typically manifests with headache, scalp tenderness, and elevated inflammatory markers.
- Cranial nerve palsy as an initial presentation of GCA is uncommon and can lead to diagnostic delays.
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