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Updated: Jul 29, 2025

Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5
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Hirschsprung-Associated Enterocolitis at a Referral Institution: A Retrospective Review

Ellen M Encisco1, Irene Isabel P Lim2, Cristine S Velazco3

  • 1Colorectal Center, Division of Pediatric General and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Journal of Pediatric Surgery
|May 23, 2023
PubMed
Summary

Hirschsprung-associated enterocolitis (HAEC) is a serious complication of Hirschsprung disease (HD). This study found a lower incidence of HAEC in patients receiving Botulinum toxin (Botox) injections, suggesting a potential preventative role.

Keywords:
Botulinum toxinHirschsprung diseaseHirschsprung-associated enterocolitis

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