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Updated: Jul 29, 2025

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management
Published on: March 15, 2024
The role of peripheral nerve stimulation in refractory non-operative chronic knee osteoarthritis
Christian T Vangeison1, Daniel J Bintrim2, Jackson Helms3
1Baylor College of Medicine H. Ben Taub Department of Physical Medicine & Rehabilitation, Houston, TX 77030, USA.
Abstract:
Aim: This case series aimed to analyze the efficacy of a temporary peripheral nerve stimulation (PNS) device implanted for 60 days at 60 days post-explant for patients with non-surgical osteoarthritic knee pain. Patients & methods: 19 patients were selected for treatment with temporary PNS at an outpatient pain management clinic. Results: Patients demonstrated improvement in their knee pain from baseline post-temporary PNS explant (p = 0.973). Conclusion: Temporary PNS serves as a promising therapy for patients with limited options for therapy, necessitating further high-quality studies.

