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Updated: Jul 29, 2025

Using the E1A Minigene Tool to Study mRNA Splicing Changes
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Differential functions of the KRAS splice variants

Juan Kochen Rossi1, Cristina Nuevo-Tapioles1, Mark R Philips1

  • 1Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY, U.S.A.

Biochemical Society Transactions
|May 24, 2023
PubMed
Summary

KRAS proteins are key in cell signaling and cancer. This review explores the distinct roles of KRAS4A and KRAS4B splice variants, highlighting KRAS4A

Keywords:
KRASKRAS4AKRAS4Balternative splicingevolutiononcogene

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