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New onset asthma during pregnancy: two case reports
Paula S Schriek1, Saar A Bendien1, Hanneke A Feitsma2
1Department of Respiratory Medicine, Haga Teaching Hospital, The Hague, South Holland, 2545AA, The Netherlands.
F1000Research
|May 24, 2023
Summary
New onset asthma during pregnancy is rare but possible, often triggered by respiratory infections like Mycoplasma pneumoniae. Early diagnosis and treatment ensure good outcomes for mother and baby.
Area of Science:
- Pulmonology
- Obstetrics
- Infectious Diseases
Background:
- Asthma is a common chronic respiratory disease, but new onset during pregnancy is infrequently reported.
- Pregnancy can alter asthma presentation and management, necessitating careful diagnostic approaches.
Observation:
- Two cases of new onset asthma during pregnancy are presented, following respiratory tract infections.
- One case involved Mycoplasma pneumoniae infection, the other a combined respiratory syncytial virus and rhinovirus infection.
Findings:
- Patients presented with acute asthma exacerbation symptoms without prior asthma history.
- Diagnosis was confirmed by spirometry showing significant reversibility and elevated fractional exhaled nitric oxide (FeNO).
- Prompt treatment with oxygen, systemic corticosteroids, and inhaled therapy resulted in favorable maternal and neonatal outcomes.
Implications:
- New onset asthma should be considered in pregnant patients with respiratory symptoms, especially after Mycoplasma infection.
- Diagnostic tools like FeNO and blood eosinophils aid in diagnosing asthma during pregnancy.
- Timely intervention is crucial for managing pregnancy-associated asthma exacerbations effectively.
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