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A Concise Synthetic Approach to Highly Reactive Click-to-Release Trans-Cyclooctene Linkers

Bing Liu1, Wolter Ten Hoeve2, Ron M Versteegen3

  • 1Tagworks Pharmaceuticals, Toernooiveld 1, 6525 ED, Nijmegen, The Netherlands.

Chemistry (Weinheim an Der Bergstrasse, Germany)
|May 24, 2023
PubMed

Keywords:
cleavable linkersclick chemistryiodolactonizationpyridazine eliminationtrans-cyclooctene

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