Toe Web Infections, the Microbiome, and Toe Web Psoriasis: A Review

Area of Science:

• Dermatology
• Microbiology
• Human Anatomy

Background:

• The toe web space presents unique anatomical and physiological conditions.
• It harbors a distinct skin microbiome that influences health and disease.
• Intertrigo and infections are common, but other conditions can mimic these.

Approach:

• A comprehensive literature review was conducted using multiple databases.
• Clinical observations and photographic evidence were incorporated.
• Keywords included toe web infections, microbiome, and psoriasis.

Key Points:

• Understanding the normal toe web microbiome is crucial for diagnosing infections.
• Factors contributing to toe web infections and their complications were analyzed.
• Toe web psoriasis is an uncommon condition often misdiagnosed as tinea pedis.

Conclusions:

• The toe web space is a unique anatomical area susceptible to various conditions.
• Microbiome alterations play a significant role in toe web infections.
• Recognizing atypical presentations like toe web psoriasis is essential for effective treatment.