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Cardiac Catheterization III: Left Heart Catheterization

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Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...

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Related Experiment Video

Updated: Jul 29, 2025

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation

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Published on: February 28, 2012

Left Bundle Branch Area Defibrillator (LBBAD): A First-in-Human Feasibility Study.

Wim L H Huybrechts¹, Marco Bergonti², Johan B Saenen¹

¹Department of Cardiology, University Hospital Antwerp, Edegem, Belgium; Department GENCOR-Heart Rhythm Disorders, University of Antwerp, Antwerp, Belgium.

JACC. Clinical Electrophysiology

|May 24, 2023

Summary

Left bundle branch area (LBBA) defibrillator (LBBAD) implantation is a feasible but complex procedure. This study demonstrated successful LBBAD implantation in 60% of patients, with no complications, paving the way for further development.

Keywords:

conduction system pacing first-in-human implantable cardioverter-defibrillator left bundle branch area defibrillation left bundle branch area pacing

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Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Published on: August 16, 2021

Area of Science:

Cardiology
Electrophysiology
Medical Device Technology

Background:

Left bundle branch area (LBBA) pacing is an emerging technique with potential benefits for patients requiring pacemakers and implantable cardioverter-defibrillators (ICDs).
Implanting ICD leads in the LBBA may reduce lead burden, potentially enhancing safety and reducing costs.
LBBA positioning for ICD leads has not been previously documented.

Purpose of the Study:

To assess the safety and feasibility of implanting an LBBA ICD lead.
To evaluate acute performance parameters of LBBA ICD lead implantation.

Main Methods:

A prospective, single-center feasibility study was conducted.
LBBA ICD lead implantation was attempted in patients indicated for an ICD.
Acute pacing parameters, electrocardiography data, and defibrillation testing were performed.

Main Results:

LBBA defibrillator (LBBAD) implantation was achieved in 3 out of 5 (60%) patients.
Successful left bundle or septal capture was achieved in 2/3 patients.
Successful defibrillation testing was performed in all 3 patients, with no lead-related complications.

Conclusions:

First-in-human evaluation indicates feasibility of LBBAD implantation.
Current implantation techniques are complex and time-consuming.
Further technological advancements and long-term outcome evaluations are warranted.