Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Risk and protective factors for musculoskeletal injury in youth track and field: a methodological scoping review.

BMC sports science, medicine & rehabilitation·2026
Same author

Cross-study analysis identifies estrogen depletion and exposure duration as key determinants of bisphenol A transcriptomic potency in MCF-7 cells.

Toxicology reports·2026
Same author

Effects of plyometric training on performance-related metrics in track and field athletes: a systematic review and meta-analysis of randomized controlled trials, with preliminary evidence on injury prevention.

BMC sports science, medicine & rehabilitation·2026
Same author

Dermatologic conditions associated with HIV among US adults across different racial and ethnic groups: A retrospective cohort study using TriNetX.

Journal of the American Academy of Dermatology·2026
Same author

Evaluation of Type 1 Error Rates in Duplex Sequencing for Mutagenicity Testing Using Vehicle Control Data and Simulation Analyses.

Environmental and molecular mutagenesis·2026
Same author

Prevalence and incidence of fibromyalgia and associated severity in the United States using MarketScan.

Pain reports·2026

Related Experiment Video

Updated: Jul 29, 2025

Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models
10:04

Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models

Published on: March 13, 2018

12.1K

Radioactive Seed Localization for Non-Breast Tissue Excision.

Andrew Williams1, Nathan Richmond2, Alan A Thomay3

  • 1School of Medicine, West Virginia University, Morgantown, WV, USA.

The American Surgeon
|May 24, 2023
PubMed
Summary

Radioactive seed localization (RSL) effectively tags non-palpable lymph nodes and masses for surgical removal. This technique, initially for breast cancer, shows promise in various non-breast cancer surgeries, improving tissue excision accuracy.

Keywords:
non-palpable lymph nodeotherradioactive seed localizationsurgical oncology

More Related Videos

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model
09:29

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model

Published on: March 20, 2020

17.9K
In Vivo Imaging to Measure Spontaneous Lung Metastasis of Orthotopically-injected Breast Tumor Cells
08:36

In Vivo Imaging to Measure Spontaneous Lung Metastasis of Orthotopically-injected Breast Tumor Cells

Published on: June 23, 2022

1.7K

Related Experiment Videos

Last Updated: Jul 29, 2025

Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models
10:04

Radionuclide-fluorescence Reporter Gene Imaging to Track Tumor Progression in Rodent Tumor Models

Published on: March 13, 2018

12.1K
Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model
09:29

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model

Published on: March 20, 2020

17.9K
In Vivo Imaging to Measure Spontaneous Lung Metastasis of Orthotopically-injected Breast Tumor Cells
08:36

In Vivo Imaging to Measure Spontaneous Lung Metastasis of Orthotopically-injected Breast Tumor Cells

Published on: June 23, 2022

1.7K

Area of Science:

  • Oncology
  • Surgical Innovation
  • Medical Imaging

Background:

  • Lymph nodes are frequent sites for cancer recurrence.
  • Distinguishing lymphatic tissue from surrounding tissues during surgery is challenging.
  • Radioactive seed localization (RSL) is a technique used in breast surgery to tag tissue for intraoperative identification.

Purpose of the Study:

  • To evaluate the efficacy and applicability of RSL in non-breast cancer surgeries.
  • To assess the use of RSL for localizing and excising non-palpable lymph nodes and masses in diverse cancer types.

Main Methods:

  • Retrospective case series of 42 non-breast cancer patients who underwent RSL.
  • Analysis of pathology results to determine tissue findings (benign, malignant, other).
  • Inclusion criteria focused on patients undergoing RSL for non-breast related indications.

Main Results:

  • Pathology revealed benign findings in 47.62% of patients, toxoplasma in 2.38%, non-necrotizing granulomatous disease in 4.76%, and malignancy in 45.24%.
  • Two patients had non-lymphatic tissue (abdominal wall, lumbar region) successfully localized and excised using RSL.
  • The technique proved effective in identifying and removing non-palpable lesions.

Conclusions:

  • Radioactive seed localization is a versatile and effective method for localizing and excising non-palpable lymph nodes and masses in non-breast cancer cases.
  • RSL demonstrates broad utility beyond breast surgery, aiding in accurate tissue identification and removal.
  • The study supports the expanded application of RSL in oncologic surgery for various cancer types.